Key result
National rotavirus vaccine introduction in Brazil was followed by a predominance of the G2P[4] strain, with G2 detection rates reaching 91% in early 2006.
Why the study?
Does national rotavirus vaccine introduction alter the distribution of rotavirus serotypes/genotypes in northern Brazil?
Population
1286 rotavirus strains collected in northern Brazil
Comparison
National rotavirus vaccine introduction vs Pre-vaccine period (1981-2005)
Design
Cohort
Follow-up
27 years (1981-2008)
Authors
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May indicate vaccine-associated G2P[4] predominance in northern Brazil; leaves open need for ongoing surveillance to guide vaccine strain selection.
Observational (n=1,286)
Does national rotavirus vaccine introduction alter the distribution of rotavirus serotypes/genotypes in northern Brazil?
Following the introduction of the rotavirus vaccine in Brazil, there was a predominance of the G2P[4] strain, highlighting the need for continuous surveillance.
Oliveira et al. (2012) conducted an observational in Rotavirus infection (n=1,286). National rotavirus vaccine introduction vs. Pre-vaccine period (1981-2005) was evaluated on Distribution of rotavirus serotypes/genotypes. National rotavirus vaccine introduction in Brazil was followed by a predominance of the G2P[4] strain, with G2 detection rates reaching 91% in early 2006.
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