Key result
Human parechovirus type 5 (PeV-A5) infection in a neonate presented as a sepsis-like syndrome and resulted in a favorable clinical outcome with mild neurological impairment at 7 days.
Why the study?
Most parechovirus A type 5 infections present with gastrointestinal syndromes, whereas sepsis-like illness has been reported only anecdotally.
Design
Case report
Follow-up
7 days
Authors
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Supports PeV testing in neonatal sepsis-like illness to limit antibiotics; leaves open need for larger studies.
Case Report (n=1)
This first reported case in Italy of PeV-A5 neurological infection in a neonate highlights the importance of ruling out enterovirus/PeV infection in infants with unexplained fever or sepsis-like syndrome to avoid unnecessary antibiotics.
Piralla et al. (2019) conducted a case report in Human parechovirus type 5 (PeV-A5) neurological infection (n=1). Human parechovirus type 5 (PeV-A5) infection was evaluated on Clinical outcome. Human parechovirus type 5 (PeV-A5) infection in a neonate presented as a sepsis-like syndrome and resulted in a favorable clinical outcome with mild neurological impairment at 7 days.
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