Key result
Visit-to-visit blood pressure variability is a confirmed prognostic predictor for cardiovascular events and target organ damage across a wide spectrum of clinical populations.
Why the study?
Does visit-to-visit blood pressure variability predict cardiovascular events and target organ damage?
Does visit-to-visit blood pressure variability predict cardiovascular events and target organ damage?
Answers are grounded in this paper and cite their sources.
Visit-to-visit blood pressure variability is an important predictor of cardiovascular events and target organ damage, highlighting the need for prospective studies on treatments that reduce this variability.
PURPOSE OF REVIEW: Recent data have highlighted the shortcomings of the usual blood pressure hypothesis in posthoc analyses of randomized controlled trials led in populations at high cardiovascular risk and have emphasized the importance of an increased visit-to-visit variability of blood pressure in predicting cardiovascular events. RECENT FINDINGS: Over the last 2 years, the prognostic value of visit-to-visit blood pressure variability has been substantially confirmed in a wide spectrum of clinical populations, in studies investigating both cardiovascular outcomes and target organ damage. SUMMARY: There is an obvious need to design studies to prospectively determine the causes of increased visit-to-visit blood pressure variability, its best estimate and whether or not treatments that reduce blood pressure variability (and to what extent/target) improve clinical outcome.
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Rossignol et al. (2012) conducted a review in Cardiovascular and renal diseases. Visit-to-visit blood pressure variability was evaluated on Cardiovascular events and target organ damage. Visit-to-visit blood pressure variability is a confirmed prognostic predictor for cardiovascular events and target organ damage across a wide spectrum of clinical populations.
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