Key result
Increased visit-to-visit blood pressure variability is associated with a higher risk of future cardiovascular events and mortality in patients with reduced ejection fraction.
Why the study?
Data regarding the visit-to-visit blood pressure variability hypothesis have been inconsistent in post-hoc analyses, prompting a review of its limitations and prognostic significance in populations at high risk of reduced ejection fraction.
Visit-to-visit blood pressure variability serves as a prognostic indicator for cardiovascular events and mortality in high-risk patients, highlighting the importance of consistent blood pressure control.
Answers are grounded in this paper and cite their sources.
Highlights the need for consistent blood pressure control rather than just absolute targets; leaves open how to standardize.
Visit-to-visit variability (VVV) of blood pressure (BP) can facilitate in predicting future reduced ejection fractions cases. In the recent past, the prognostic significance of visitto-visit variability of BP has been examined widely in patients with a high risk of cardiovascular disease. The findings of numerous investigations have indicated that increased visit-to-visit variability of blood pressure can lead to better estimation or proper treatments that can minimize blood pressure variability and associated risks while enhancing clinical outcomes. However, inconsistent data of the visit-to-visit hypothesis in the post-hoc analysis have also been explored. Therefore, this review discusses recent analysis, background, and reports of the limitations of visit-to-visit blood pressure variability (VVV-BP) and the prognostic significance of visit-to-visit blood pressure variability in populations at high risk of reduced ejection fractions in predictions of future vascular diseases. The role of the antihypertensive drugs is highlighted while describing the clinical implications and future research directions.
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Juvenal et al. (2022) conducted a review in Reduced ejection fraction and cardiovascular disease. Visit-to-visit blood pressure variability was evaluated. Increased visit-to-visit blood pressure variability is associated with a higher risk of future cardiovascular events and mortality in patients with reduced ejection fraction.
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