Key result
Prior infection with feline calicivirus strains provided cross-protection against pathogenic challenge at 3 months, with clinical signs in 0% of specific-pathogen-free and 21.4% of conventional cats.
Why the study?
Does initial infection with feline calicivirus strains provide cross-protection against subsequent challenge with pathogenic strains in cats?
Does initial infection with feline calicivirus strains provide cross-protection against subsequent challenge with pathogenic strains in cats?
Initial infection with feline calicivirus provides significant clinical cross-protection and reduces the duration of viral excretion upon subsequent challenge with pathogenic strains.
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Supports FCV cross-protection models in cats; leaves open translation to vaccines or natural settings.
Povey et al. (1975) studied Feline calicivirus infection (n=58). Initial infection with feline calicivirus strains was evaluated on Clinical signs upon challenge. Prior infection with feline calicivirus strains provided cross-protection against pathogenic challenge at 3 months, with clinical signs in 0% of specific-pathogen-free and 21.4% of conventional cats.
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