Key result
Intramuscular administration of an attenuated feline calicivirus vaccine induced protective immunity, preventing severe pneumonia and death which occurred in 100% of control cats after viral challenge.
Why the study?
Does intramuscular administration of an attenuated FCV prevent severe pneumonia and death in specific-pathogen-free cats exposed to virulent FCV?
Does intramuscular administration of an attenuated FCV prevent severe pneumonia and death in specific-pathogen-free cats exposed to virulent FCV?
Intramuscular administration of an attenuated feline calicivirus induces protective immunity against virulent FCV challenge in cats.
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Supports FCV vaccine research in cats; leaves open translation to clinical practice pending field trials.
Kahn et al. (1976) studied Feline caliciviral disease. Attenuated feline calicivirus (FCV) vaccine vs. Control (unvaccinated) was evaluated on Severe pneumonia and death after virulent FCV challenge. Intramuscular administration of an attenuated feline calicivirus vaccine induced protective immunity, preventing severe pneumonia and death which occurred in 100% of control cats after viral challenge.
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