Key result
Coronary flow reserve measured by contrast-enhanced transesophageal Doppler echocardiography was significantly lower in patients with type 2 diabetes compared to controls (1.4 vs 2.1, p<0.01).
Why the study?
Does contrast-enhanced transesophageal Doppler echocardiography measurement of coronary sinus flow reserve detect microvascular dysfunction in patients with type 2 diabetes mellitus?
Population
29 patients with angiographically normal epicardial coronary arteries, including 16 patients with type 2…
Comparison
Coronary flow reserve measurement using coronary… vs Non-diabetic control patients undergoing the…
Design
Cross-sectional, One experienced investigator who was unaware of the other…
Authors
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Supports noninvasive CFR assessment for diabetic microvascular dysfunction; hypothesis-generating and should not yet change practice.
Observational (n=29)
Does contrast-enhanced transesophageal Doppler echocardiography measurement of coronary sinus flow reserve detect microvascular dysfunction in patients with type 2 diabetes mellitus?
Absolute Event Rate: 1.4% vs 2.1%
p-value: p=<0.01
Contrast-enhanced transesophageal Doppler echocardiography measurement of coronary sinus flow reserve can noninvasively detect diabetic microvascular dysfunction.
Nishino et al. (2006) conducted an observational in Type 2 diabetes mellitus (n=29). Type 2 diabetes mellitus vs. Non-diabetic controls was evaluated on Coronary flow reserve (CFR) (p=<0.01). Coronary flow reserve measured by contrast-enhanced transesophageal Doppler echocardiography was significantly lower in patients with type 2 diabetes compared to controls (1.4 vs 2.1, p<0.01).