Key result
Increasing time delay while increasing control strategies (vaccination, treatment, culling) decreases the burden of foot and mouth disease in simulation models.
Mathematical modeling suggests that combining effective control strategies with appropriate time delays can mitigate the burden of foot and mouth disease.
Should not yet guide FMD control policies; hypothesis-generating simulation extends models but requires field validation.
We develop a delay ordinary differential equation model that captures the effects of prophylactic vaccination, reactive vaccination, prophylactic treatment and reactive culling on the spread of foot and mouth disease (FMD) with time delays. Simulation results from the study suggest that increasing time delay while increasing the control strategies decreases the burden of FMD. Further, the results reveal, that decreasing time delay while decreasing the control strategies increases the burden of FMD. The intermediate scenarios of either (i) increasing time delay while decreasing control or (ii) decreasing time delay while increasing control have intermediate effects on burden reduction. Thus, the implementation of effective control strategies combination can play an important role in mitigating against the FMD burden.
No takes yet. Share an insight, caveat, or question.
Tessema et al. (2019) studied Foot and mouth disease. Control strategies (vaccination, treatment, culling) with time delays was evaluated on Burden of FMD. Increasing time delay while increasing control strategies (vaccination, treatment, culling) decreases the burden of foot and mouth disease in simulation models.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: