Key result
Patients with postoperative complications had a three-fold elevation in procalcitonin on days 1 and 5, and a two-fold elevation in IL-6 on day 7 compared to those without complications.
Why the study?
Do elevated levels of procalcitonin, IL-6, and TNF-a predict postoperative complications in patients undergoing major thoracic surgery?
Population
37 patients undergoing thoracotomy for lung resection
Comparison
Measurement of serum procalcitonin, interleukin… vs Preoperative values and patients without…
Design
Cohort
Follow-up
7 days
Authors
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May aid early detection of complications after thoracic surgery; hypothesis-generating and requires prospective validation before adoption.
Observational (n=37)
No
Do elevated levels of procalcitonin, IL-6, and TNF-a predict postoperative complications in patients undergoing major thoracic surgery?
p-value: p=<0.05
Elevated procalcitonin on postoperative day one and IL-6 on day seven are promising early markers of postoperative complications following major thoracic surgery.
Hıdır Eşme (2012) conducted an observational in Major thoracic surgery (lung resection) (n=37). Elevated postoperative procalcitonin and IL-6 levels vs. Patients without postoperative complications was evaluated on Postoperative complications (p=<0.05). Patients with postoperative complications had a three-fold elevation in procalcitonin on days 1 and 5, and a two-fold elevation in IL-6 on day 7 compared to those without complications.
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