Key result
Postoperative cardiac or infectious complications after major pulmonary resection were associated with higher peak levels and a slower decrease of procalcitonin, BNP, and IL-6.
Why the study?
Does the monitoring of procalcitonin, brain natriuretic peptide, and interleukin-6 predict postoperative infectious or cardiac complications in patients undergoing major pulmonary resection?
Population
22 patients admitted with lung cancer undergoing major pulmonary resection
Comparison
Postoperative monitoring of procalcitonin, brain… vs Patients without postoperative complications
Design
Cohort
Follow-up
5 days postoperatively
Authors
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May support serial biomarker monitoring for early complication detection after pulmonary resection; hypothesis-generating and should not yet change practice.
Observational (n=22)
Does the monitoring of procalcitonin, brain natriuretic peptide, and interleukin-6 predict postoperative infectious or cardiac complications in patients undergoing major pulmonary resection?
Elevated peak levels and slower decreases of procalcitonin, BNP, and IL-6 are associated with postoperative infectious and cardiac complications after major pulmonary resection.
Hoksch et al. (2006) conducted an observational in Lung cancer (n=22). Cardiac or infectious complications vs. No complications was evaluated on Peak levels and trajectory of procalcitonin, brain natriuretic peptide, C-reactive peptide, and interleukin-6. Postoperative cardiac or infectious complications after major pulmonary resection were associated with higher peak levels and a slower decrease of procalcitonin, BNP, and IL-6.
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