Key result
Hypertensive patients had a roughly 40% increase in mean carotid intimal-medial thickness compared to normotensive controls (0.95 mm vs 0.68 mm, p<0.05), which significantly correlated with left ventricular mass index.
Why the study?
Does carotid intimal-medial thickness correlate with left ventricular mass index in hypertensive patients?
Population
110 adults aged 40 years or older, including 72 hypertensive patients and 38 normotensive controls without a…
Comparison
Hypertension (observational exposure) vs Normotensive controls
Design
Cross-sectional
Authors
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Supports concurrent carotid and cardiac remodeling in hypertension; leaves open causal links and outcome impact.
Cross-Sectional (n=110)
No
Does carotid intimal-medial thickness correlate with left ventricular mass index in hypertensive patients?
Mean Difference: 0.27
Absolute Event Rate: 0.95% vs 0.68%
p-value: p=<0.05
Carotid intimal-medial thickness is significantly increased in hypertensive patients and correlates positively with left ventricular mass index, suggesting a simultaneous progression of atherosclerosis and left ventricular hypertrophy.
Kwak et al. (1998) conducted a cross-sectional in Hypertension and Left Ventricular Hypertrophy (n=110). Hypertension vs. Normotensive controls was evaluated on Mean carotid intimal-medial thickness (IMT) of all 12 segments (MD 0.27, p=<0.05). Hypertensive patients had a roughly 40% increase in mean carotid intimal-medial thickness compared to normotensive controls (0.95 mm vs 0.68 mm, p<0.05), which significantly correlated with left ventricular mass index.
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