Key result
In patients undergoing mitral valve repair for functional mitral regurgitation, 5-year freedom from mortality and heart failure readmission was 64% in ESRD versus 52% in controls (P=1).
Why the study?
Does renal function status affect outcomes after mitral valve repair for medically refractory functional mitral regurgitation in patients with advanced heart failure?
Cohort (n=208)
Does renal function status affect outcomes after mitral valve repair for medically refractory functional mitral regurgitation in patients with advanced heart failure?
Absolute Event Rate: 64% vs 52%
p-value: p=1
Mitral valve repair for functional mitral regurgitation in advanced heart failure improves hemodynamics across all renal function stages, with ESRD patients demonstrating better long-term event-free survival compared to those with late-stage chronic kidney disease not on dialysis.
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Similar event-free survival in ESRD; leaves open whether renal status modifies benefit after mitral valve repair in advanced HF.
Kainuma et al. (2012) conducted a cohort in Medically Refractory Functional Mitral Regurgitation and Advanced Heart Failure (n=208). End-stage renal disease on hemodialysis vs. eGFR ≥30 mL/min/1.73 m2 (control) was evaluated on Freedom from mortality and heart failure readmission at 5 years (p=1). In patients undergoing mitral valve repair for functional mitral regurgitation, 5-year freedom from mortality and heart failure readmission was 64% in ESRD versus 52% in controls (P=1).
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