Key result
Defibrillation thresholds significantly increased in the first 12 weeks following ICD implantation for both epicardial (3.4 to 7.9 J; P=0.05) and transvenous (10.3 to 16.1 J; P=0.004) lead systems.
Why the study?
Does the defibrillation threshold change over the first year following ICD implantation in patients without clinical or device changes?
Population
61 patients prospectively enrolled undergoing epicardial or non-thoracotomy/transvenous implantable…
Design
Cohort
Follow-up
52 weeks
Authors
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Transient DFT rise early after ICD implantation warrants caution in testing or programming; leaves open need for prospective outcome studies.
Observational (n=61)
Does the defibrillation threshold change over the first year following ICD implantation in patients without clinical or device changes?
p-value: p=0.05 and 0.004
Defibrillation thresholds exhibit a transient, significant rise during the first 12 weeks post-ICD implantation, likely due to electrode-tissue interface changes, before partially returning to baseline.
Poole et al. (1995) conducted an observational in Implantable cardioverter defibrillator (ICD) therapy (n=61). ICD implantation vs. Baseline (at implant) was evaluated on Defibrillation threshold (DFT) changes over the first year (p=0.05 and 0.004). Defibrillation thresholds significantly increased in the first 12 weeks following ICD implantation for both epicardial (3.4 to 7.9 J; P=0.05) and transvenous (10.3 to 16.1 J; P=0.004) lead systems.
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