Key result
Pre-eclampsia was associated with significantly lower maternal plasma beta-endorphin levels during labour compared to healthy controls (22.73 vs 48.38 pmol/l; p<0.001).
Why the study?
Are maternal plasma beta-endorphin levels altered in pre-eclamptic women during labour compared to healthy controls?
Case-Control (n=50)
Are maternal plasma beta-endorphin levels altered in pre-eclamptic women during labour compared to healthy controls?
Absolute Event Rate: 22.73% vs 48.38%
p-value: p=<0.001
Maternal plasma beta-endorphin levels are significantly reduced in pre-eclampsia during labour and inversely correlate with blood pressure severity.
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Should not yet alter labour management; hypothesis-generating for beta-endorphin pathways in pre-eclampsia.
M. R. M. Elghorori (2005) conducted a case-control in Pre-eclampsia (n=50). Pre-eclampsia vs. Healthy women was evaluated on Maternal plasma beta-endorphin concentration (p=<0.001). Pre-eclampsia was associated with significantly lower maternal plasma beta-endorphin levels during labour compared to healthy controls (22.73 vs 48.38 pmol/l; p<0.001).
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