Key result
Circulating epinephrine and norepinephrine are avidly absorbed and stored by the heart muscle but not by skeletal muscle in dogs, and cardiac sympathetic nerve stimulation augments myocardial norepinephrine.
Authors
Loading...
Should not alter clinical management; extends experimental evidence on myocardial catecholamine handling but requires human validation.
Raab et al. (1955) studied this question. Circulating epinephrine and norepinephrine, sympathetic nerve stimulation, and sympatholytic drugs vs. Skeletal muscle / no stimulation was evaluated on Absorption and storage of epinephrine and norepinephrine. Circulating epinephrine and norepinephrine are avidly absorbed and stored by the heart muscle but not by skeletal muscle in dogs, and cardiac sympathetic nerve stimulation augments myocardial norepinephrine.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: