Key result
The Roche digoxin 'On Line' procedure demonstrated the lowest overall interference by digoxin-like immunoreactive factor compared to Stratus and TDx methods in susceptible patient specimens.
Why the study?
Does the Roche digoxin "On Line" procedure reduce interference by digoxin-like immunoreactive factor compared to established methods in pediatric and other high-DLIF specimens?
Population
Specimens from a pediatric population, neonates, women with second/third trimester pregnancies, and patients…
Comparison
Roche digoxin "On Line" immunoassay procedure vs Abbott TDx, American Dade Stratus, and…
Design
Other
Authors
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May favor Roche assay to minimize DLIF interference in susceptible specimens; leaves open prospective validation before routine pediatric adoption.
Cross-Sectional
Does the Roche digoxin "On Line" procedure reduce interference by digoxin-like immunoreactive factor compared to established methods in pediatric and other high-DLIF specimens?
The Roche digoxin "On Line" immunoassay demonstrates low DLIF interference and requires small specimen volumes, making it highly suitable for monitoring digoxin levels in pediatric patients.
Jiang et al. (1995) conducted a cross-sectional in Patients likely to contain digoxin-like immunoreactive factor (DLIF). Roche digoxin 'On Line' procedure vs. Abbott TDx, American Dade Stratus, and COBAS-FARA methods was evaluated on Interference by digoxin-like immunoreactive factor (DLIF). The Roche digoxin 'On Line' procedure demonstrated the lowest overall interference by digoxin-like immunoreactive factor compared to Stratus and TDx methods in susceptible patient specimens.
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