Key result
Atriopeptin III and related atrial natriuretic peptide hormones strongly elevated the level of cyclic GMP in three neural tumor cell lines, reaching a maximum in 30-40 minutes.
Atrial natriuretic hormones strongly elevate cyclic GMP in neural cells, suggesting a potential role for these hormones in the nervous system.
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No immediate clinical implications; extends natriuretic peptide effects to neural cells and leaves open in vivo roles.
Friedl et al. (1986) studied this question. Atriopeptin III and related atrial natriuretic peptide hormones was evaluated on Intracellular concentration of cyclic GMP. Atriopeptin III and related atrial natriuretic peptide hormones strongly elevated the level of cyclic GMP in three neural tumor cell lines, reaching a maximum in 30-40 minutes.
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