Key result
An 8000 mg propranolol overdose caused sudden arrhythmias, cardiac failure, and convulsions that responded to ventilator support, transvenous pacing, and massive doses of isoprenaline.
Severe propranolol overdose presenting with arrhythmias, heart failure, and convulsions can be successfully managed with ventilator support, transvenous pacing, and high-dose isoprenaline.
High-dose isoprenaline with pacing may aid recovery in severe propranolol overdose; leaves open need for systematic evaluation.
A 14-year-old boy who ingested 8000 mg of propranolol developed sudden onset of arrhythmias, cardiac failure and convulsions. He responded to ventilator support, transvenous pacing, and massive dosage of isoprenaline. The clinical features and management of propranolol overdosage are outlined.
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Tynan et al. (1981) studied this question. An 8000 mg propranolol overdose caused sudden arrhythmias, cardiac failure, and convulsions that responded to ventilator support, transvenous pacing, and massive doses of isoprenaline.
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