Key result
Early cardiac phosphocreatine/beta-ATP ratios in patients with myocardial stunning after reperfusion were not significantly different from healthy controls (1.51 vs 1.61, p=0.17).
Why the study?
Are cardiac high energy phosphates depleted in postischemic stunned human myocardium compared to healthy controls?
Observational (n=37)
Are cardiac high energy phosphates depleted in postischemic stunned human myocardium compared to healthy controls?
Absolute Event Rate: 1.51% vs 1.61%
p-value: p=0.17
Myocardial PCr/ATP ratios are normal in patients with myocardial stunning after reperfusion, suggesting that relative cardiac high energy phosphates are not depleted in stunned human myocardium.
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Supports preserved high-energy phosphates in stunned myocardium; hypothesis-generating for mechanisms of postischemic dysfunction.
Filho et al. (1997) conducted an observational in Myocardial stunning after reperfusion (n=37). First anterior myocardial infarction with successful reperfusion vs. Healthy control subjects was evaluated on Cardiac phosphocreatine (PCr)/beta-adenosine triphosphate (beta-ATP) ratio (p=0.17). Early cardiac phosphocreatine/beta-ATP ratios in patients with myocardial stunning after reperfusion were not significantly different from healthy controls (1.51 vs 1.61, p=0.17).
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