Key result
Early surgical repair of coarctation of the aorta was associated with a higher prevalence of systolic arterial pressure above the 95th percentile compared to healthy controls (18.5% vs 0%, p<0.01).
Why the study?
Does early surgical repair of coarctation of the aorta normalize elastic properties of the aortic wall compared to healthy controls?
Observational (n=81)
Does early surgical repair of coarctation of the aorta normalize elastic properties of the aortic wall compared to healthy controls?
Absolute Event Rate: 18.5% vs 0%
p-value: p=<0.01
Elastic properties of the aortic wall remain impaired even after early neonatal surgical repair of coarctation of the aorta, suggesting a systemic vascular pathology.
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Altered aortic elasticity after infant coarctation repair may persist; leaves open need for targeted long-term monitoring studies.
Sinelnikov et al. (2017) conducted an observational in Coarctation of the aorta (n=81). Surgical repair of coarctation of the aorta in infancy vs. Patients without any congenital heart pathology was evaluated on Systolic arterial pressure above 95 percentiles (p=<0.01). Early surgical repair of coarctation of the aorta was associated with a higher prevalence of systolic arterial pressure above the 95th percentile compared to healthy controls (18.5% vs 0%, p<0.01).
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