Key result
Plasma Ang-2 and P-selectin levels were significantly higher in active SLE patients compared to inactive patients and healthy controls (p < 0.001), correlating positively with SLEDAI scores.
Population
Active systemic lupus erythematosus (SLE) patients, inactive SLE patients, and healthy normal control subjects
Design
Cross-sectional
Authors
Loading...
Ang-2 and P-selectin associate with SLE activity; hypothesis-generating for biomarkers, prospective validation required before clinical use.
Cross-Sectional
p-value: p=< 0.001
Angiopoietin-2 and P-Selectin are significantly elevated in active SLE and correlate with disease activity, suggesting Ang-2 may be a useful marker for assessing SLE activity.
Salama et al. (2012) conducted a cross-sectional in Systemic lupus erythematosus. Plasma Angiopoietin-2 (Ang-2) and P-Selectin levels vs. Inactive SLE patients and healthy controls was evaluated on Mean level of Plasma Ang-2 and P-selectin (p=< 0.001). Plasma Ang-2 and P-selectin levels were significantly higher in active SLE patients compared to inactive patients and healthy controls (p < 0.001), correlating positively with SLEDAI scores.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: