Key result
Right atrial septal pacing shortened atrial conduction time (P<0.0005), and optimizing AV delay using surface ECG increased stroke volume by 10.9% (95% CI 5.9-15.9%) compared to nominal settings.
Why the study?
Does right atrial septal pacing and ECG-guided AV delay optimization improve atrial conduction time and stroke volume compared to standard pacing sites and nominal AV delay in patients with dual chamber pacemakers?
Population
60 patients following dual chamber pacemaker implantation, including a subgroup of 31 patients with AV block.
Comparison
Right atrial septal pacing and optimization of… vs Standard right atrial pacing sites at the right…
Design
Cohort
Authors
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May support septal pacing plus ECG AV optimization in dual-chamber devices; hypothesis-generating and requires RCTs before practice change.
Observational (n=60)
Does right atrial septal pacing and ECG-guided AV delay optimization improve atrial conduction time and stroke volume compared to standard pacing sites and nominal AV delay in patients with dual chamber pacemakers?
Mean Difference: 10.9 (95% CI 5.9–15.9)
Right atrial septal pacing and ECG-guided AV delay optimization improve atrial synchronization and systolic function in patients with dual chamber pacemakers.
Strohmer et al. (2004) conducted an observational in Patients following dual chamber pacemaker implantation (n=60). Right atrial septal pacing and AV delay optimization vs. Standard right atrial pacing and nominal AV delay was evaluated on Relative increase of echocardiographic stroke volume (SV) compared to nominal AV delay (MD 10.9%, 95% CI 5.9-15.9). Right atrial septal pacing shortened atrial conduction time (P<0.0005), and optimizing AV delay using surface ECG increased stroke volume by 10.9% (95% CI 5.9-15.9%) compared to nominal settings.
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