Key result
Single breath induction of anaesthesia using halothane, nitrous oxide, and oxygen was acceptable to 91% of outpatients, with a mean induction time of 83 seconds.
Why the study?
Does a single vital capacity breath of halothane, nitrous oxide, and oxygen provide safe and acceptable anaesthetic induction in unpremedicated outpatients?
Does a single vital capacity breath of halothane, nitrous oxide, and oxygen provide safe and acceptable anaesthetic induction in unpremedicated outpatients?
Single breath induction with halothane, nitrous oxide, and oxygen is a safe and acceptable alternative to intravenous induction in adult outpatients.
Answers are grounded in this paper and cite their sources.
May support outpatient use; hypothesis-generating without randomized safety data vs intravenous induction.
Inhalational induction of anaesthesia, using a single vital capacity breath of 4% halothane in 66% nitrous oxide and 33% oxygen was evaluated in 100 unpremedicated outpatients. The technique was found to be acceptable to most (91%) of the patients studied, with a mean (SD) induction time (measured from beginning of inspiration to loss of 'eyelash reflex') of 83(21) seconds. Relative cardiovascular stability was a notable finding of the technique, with a slight decrease in the mean arterial pressure of only 10%. Anaesthetic induction time was unaffected by age, weight or smoking habits. The technique of single breath induction is therefore proposed as a safe and acceptable alternative to intravenous induction in co-operative adult patients.
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Wilton et al. (1986) studied Outpatients requiring anaesthesia (n=100). Single vital capacity breath of halothane, nitrous oxide and oxygen was evaluated on Acceptability of the technique. Single breath induction of anaesthesia using halothane, nitrous oxide, and oxygen was acceptable to 91% of outpatients, with a mean induction time of 83 seconds.
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