Key result
Short-term parenteral amiodarone therapy was associated with the development of torsades de pointes in an 80-year-old female with paroxysmal atrial fibrillation and acute heart failure.
Why the study?
Amiodarone widely treats atrial fibrillation with a remarkably low incidence of torsades de pointes (<1.0%), which typically occurs after long-term usage.
Does short-term parenteral amiodarone therapy cause torsades de pointes in an elderly patient with paroxysmal atrial fibrillation and acute heart failure?
Case Report (n=1)
Does short-term parenteral amiodarone therapy cause torsades de pointes in an elderly patient with paroxysmal atrial fibrillation and acute heart failure?
Short-term parenteral amiodarone can rarely cause torsades de pointes, highlighting the need for vigilance even outside of long-term usage.
Answers are grounded in this paper and cite their sources.
May rarely trigger torsades de pointes with short-term parenteral amiodarone in elderly AF/HF patients; leaves open incidence and causality.
One of the drugs that are widely used in the treatment of atrial fibrillation is amiodarone. Despite considerable prolongation of the corrected QT interval and a substantial degree of bradycardia, amiodarone exhibits a remarkably low frequency of pro-arrhythmic events and <1.0% incidence of torsades de pointes, mostly after long-term usage. We present a case of an 80-year-old female with paroxysmal atrial fibrillation accompanied by acute heart failure treated by short-term parenteral amiodarone therapy and development of torsades de pointes.
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Nenad Lakušić (2019) conducted a case report in Paroxysmal atrial fibrillation accompanied by acute heart failure (n=1). Short-term parenteral amiodarone therapy was evaluated on Development of torsades de pointes. Short-term parenteral amiodarone therapy was associated with the development of torsades de pointes in an 80-year-old female with paroxysmal atrial fibrillation and acute heart failure.
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