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Purified S-adenosyl-L-methionine: uroporphyrinogen (uro'gen) III methyl transferase (SUMT), the first methylase of the vitamin B12 pathway (from Pseudomonas denitrificans), synthesizes a type I isomer of sirohydrochlorin from uro'gen I (1).
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Scott et al. (1989) studied this question.
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