Key result
A single oral loading dose of amiodarone (1400 mg) administered after short intravenous loading resulted in marked QT prolongation, bradycardia, and torsade de pointes.
Population
1 patient with paroxysmal atrial flutter
Design
Case_report
Authors
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May warrant ECG monitoring during amiodarone loading; single case leaves generalizability and incidence open.
Case Report (n=1)
Careful monitoring is necessary during oral amiodarone loading due to the risk of QT prolongation and torsade de pointes.
Leroy et al. (1987) conducted a case report in Paroxysmal atrial flutter (n=1). Amiodarone was evaluated on Torsade de pointes. A single oral loading dose of amiodarone (1400 mg) administered after short intravenous loading resulted in marked QT prolongation, bradycardia, and torsade de pointes.
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