Key result
Cystatin C serves as a sensitive early marker of renal dysfunction and a significant predictor of cardiovascular events and target organ damage in patients with cardiovascular pathology.
Why the study?
Renal disorders frequently occur in cardiovascular diseases, but the widespread use of cystatin C as an indicator of renal function in routine clinical practice requires further study and improvement.
Does Cystatin C measurement improve the prediction of renal dysfunction and cardiovascular events in patients with cardiovascular pathology compared to standard creatinine?
Does Cystatin C measurement improve the prediction of renal dysfunction and cardiovascular events in patients with cardiovascular pathology compared to standard creatinine?
Cystatin C serves as an early, sensitive biomarker for renal dysfunction and a strong predictor of cardiovascular events across multiple cardiovascular diseases, outperforming traditional creatinine measurements.
Answers are grounded in this paper and cite their sources.
May support cystatin C for early renal and CV risk monitoring in practice; hypothesis-generating pending prospective validation over creatinine.
Disorders of the kidneys often occur in cardiovascular diseases. They are connected with the heart by complex hemodynamic and neuroendocrine bonds. The structure, functions, and possibilities of using an endogenous indicator of the functional state of the kidney - cystatin C are discussed in the article. Available data allow the use of cystatin C as a predictor of renal dysfunction in patients with cardiovascular pathology and arterial hypertension, in particular. However, the widespread use of cystatin C in routine clinical practice requires further study and improvement.
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Kuzmіnova et al. (2018) conducted a review in Cardiovascular pathology and renal dysfunction. Cystatin C was evaluated. Cystatin C serves as a sensitive early marker of renal dysfunction and a significant predictor of cardiovascular events and target organ damage in patients with cardiovascular pathology.
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