Key result
Cystatin C serves as an early, sensitive biomarker of renal dysfunction and a powerful predictor of cardiovascular events in patients with cardiovascular pathology.
Why the study?
Renal disorders frequently occur in cardiovascular diseases, but widespread clinical use of cystatin C to predict renal dysfunction requires further study.
Does cystatin C measurement improve the prediction of renal dysfunction and cardiovascular events in patients with cardiovascular pathology?
Does cystatin C measurement improve the prediction of renal dysfunction and cardiovascular events in patients with cardiovascular pathology?
Answers are grounded in this paper and cite their sources.
Cystatin C serves as an early, sensitive biomarker for renal dysfunction and a strong predictor of cardiovascular events, outperforming traditional creatinine measurements in patients with cardiovascular disease.
Disorders of the kidneys often occur in cardiovascular diseases. They are connected with the heart by complex hemodynamic and neuroendocrine bonds. The structure, functions, and possibilities of using an endogenous indicator of the functional state of the kidney - cystatin C are discussed in the article. Available data allow the use of cystatin C as a predictor of renal dysfunction in patients with cardiovascular pathology and arterial hypertension, in particular. However, the widespread use of cystatin C in routine clinical practice requires further study and improvement.
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Kuzmіnova et al. (2018) conducted a review in Cardiovascular pathology and renal dysfunction. Cystatin C was evaluated. Cystatin C serves as an early, sensitive biomarker of renal dysfunction and a powerful predictor of cardiovascular events in patients with cardiovascular pathology.
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