Key result
Ingestion of a recreational delta-8 THC gummy induced a reversible Brugada type 1 electrocardiogram pattern in a 31-year-old male.
Why the study?
Known triggers can elicit a Brugada ECG pattern without clear clinical significance, creating an urgent diagnostic and clinical dilemma.
Case Report (n=1)
Recreational use of delta-8 THC can induce a transient Brugada electrocardiogram pattern, highlighting a potential cardiac risk associated with this over-the-counter supplement.
Delta-8 THC may trigger transient Brugada pattern; case report is hypothesis-generating and leaves broader arrhythmic risk open.
Brugada electrocardiogram (ECG) pattern describes a characteristic right bundle branch block (RBBB) appearance with persistent ST-segment elevation in precordial leads V1 to V3, often associated with Brugada syndrome, a genetic sodium channelopathy, in the absence of ischemic or structural heart disease. Known triggers such as fever, electrolyte abnormalities, medications, or recreational drugs may elicit such an ECG pattern without a clear clinical significance yet creating a dilemma for clinicians providing care in the urgent setting. We present a case of reversible Brugada electrocardiogram pattern (BEP) after recreational use of delta-8-tetrahydrocannabinol (THC) and explore the need for further research on the safety of such an over-the-counter supplement.
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Jo et al. (2021) conducted a case report in Brugada electrocardiogram pattern (n=1). Recreational delta-8-tetrahydrocannabinol (THC) gummy was evaluated on Development of Brugada electrocardiogram pattern. Ingestion of a recreational delta-8 THC gummy induced a reversible Brugada type 1 electrocardiogram pattern in a 31-year-old male.
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