Key result
A rare case of fibrin-associated large B-cell lymphoma was discovered proliferating within the mural thrombus of a large iliofemoral aneurysm.
Why the study?
Fibrin-associated large B-cell lymphoma is an extremely rare EBV-associated lymphoproliferative disorder typically found incidentally, with only one prior case reported within an aneurysm mural thrombus.
Case Report (n=1)
This case report documents an extremely rare occurrence of fibrin-associated large B-cell lymphoma within an iliofemoral aneurysm.
May prompt consideration of FA-LBCL in aneurysm thrombi; leaves open questions on incidence and management.
Fibrin-associated large B-cell lymphoma (FA-LBCL) is an extremely rare, non-mass forming lymphoproliferative disorder associated with Epstein-Barr virus (EBV). It is typically discovered incidentally on histologic examination of tissue removed for unrelated reasons. The following case report presents only the second reported case in the literature of FA-LBCL found proliferating within the mural thrombus of an aneurysm.
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Zickler et al. (2025) conducted a case report in Fibrin-associated large B-cell lymphoma (FA-LBCL) in an iliofemoral aneurysm (n=1). A rare case of fibrin-associated large B-cell lymphoma was discovered proliferating within the mural thrombus of a large iliofemoral aneurysm.
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