Key result
Cardiac autonomic neuropathy, present in 66% of patients with type 2 diabetes, was associated with significantly higher resting heart rate, QTc mean, QTc max, and QTc dispersion.
Why the study?
Is cardiac autonomic neuropathy associated with increased heart rate and prolonged QTc intervals in patients with type 2 diabetes?
Population
50 patients with type 2 diabetes mellitus of more than 5-years duration and 30 age- and sex-matched controls…
Comparison
Presence of cardiac autonomic neuropathy vs Diabetics without autonomic neuropathy and…
Design
Cross-sectional
Authors
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May heighten arrhythmia risk via QTc changes; leaves open need for prospective CAN outcome trials.
Observational (n=80)
Is cardiac autonomic neuropathy associated with increased heart rate and prolonged QTc intervals in patients with type 2 diabetes?
Diabetic autonomic neuropathy is associated with increased resting heart rate, prolonged QTc intervals, and increased QTc dispersion, which may predispose to arrhythmias.
Pillai et al. (2015) conducted an observational in Type 2 diabetes mellitus (n=80). Cardiac autonomic neuropathy vs. Diabetics without autonomic neuropathy and healthy controls was evaluated on QTc interval and QTc dispersion. Cardiac autonomic neuropathy, present in 66% of patients with type 2 diabetes, was associated with significantly higher resting heart rate, QTc mean, QTc max, and QTc dispersion.
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