Key result
Intravenous isoprenaline infusions in conscious monkeys produced dose-related increases in blood flow to the heart, skeletal muscle, intestines, adipose tissue, and bone.
Why the study?
Does intravenous isoprenaline alter the distribution of cardiac output and myocardial blood flow in conscious monkeys?
Does intravenous isoprenaline alter the distribution of cardiac output and myocardial blood flow in conscious monkeys?
Intravenous isoprenaline in conscious monkeys causes dose-dependent redistribution of cardiac output, increasing flow to the heart and skeletal muscle while decreasing flow to the brain and kidneys.
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Hypothesis-generating for beta-agonist effects on regional perfusion in primates; leaves open translation to human hemodynamics.
Hoffbrand et al. (1973) studied this question. Intravenous isoprenaline infusions was evaluated on Distribution of cardiac output and myocardial blood flow. Intravenous isoprenaline infusions in conscious monkeys produced dose-related increases in blood flow to the heart, skeletal muscle, intestines, adipose tissue, and bone.
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