Why the study?
Does adenosine attenuate the rise in oxygen consumption induced by isoprenaline in isolated perfused guinea pig hearts?
Does adenosine attenuate the rise in oxygen consumption induced by isoprenaline in isolated perfused guinea pig hearts?
Adenosine attenuates cardiac muscle work and oxygen extraction during sympathetic stimulation, leading to a net inhibition of myocardial oxygen consumption despite enhancing coronary flow.
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Hypothesis-generating in isolated hearts; leaves open translation to in vivo or clinical sympathetic stress.
BERANEK et al. (1983) studied this question.
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