Key result
Platelet activation induces changes in glycoprotein expression that differ between in vitro and in vivo experimental settings.
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Urges caution extrapolating in vitro platelet glycoprotein data to patients; leaves open need for in vivo validation studies.
Keywords Platelet adhesion - platelet aggregation - GPIb - GPIIb-IIIa - receptor movement
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A 2000 study studied this question. Platelet activation induces changes in glycoprotein expression that differ between in vitro and in vivo experimental settings.
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