Key result
A purification method using Ficoll gradients and rate-zonal centrifugation achieved a nearly threefold increase in specific activity of ATPase in avian myeloblastosis virus.
Population
Avian myeloblastosis virus in high-titer viremic plasma from leukemic chickens
Design
Preclinical
Authors
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May refine retroviral enzyme prep in lab models; leaves open translation to cardiovascular research.
The study describes a rapid purification method for avian myeloblastosis virus that increases ATPase specific activity and allows for simple quantitation.
Stromberg et al. (1972) studied Avian myeloblastosis virus. Purification method using Ficoll gradients and rate-zonal centrifugation was evaluated on Specific activity of adenosine triphosphatase (ATPase). A purification method using Ficoll gradients and rate-zonal centrifugation achieved a nearly threefold increase in specific activity of ATPase in avian myeloblastosis virus.
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