Key result
Asthma did not increase mortality after coronary artery bypass graft surgery compared to controls (3.8% vs 3.8%, p=1.000), but was associated with a significantly longer intensive care unit stay.
Why the study?
No studies had specifically assessed mortality and morbidity in asthma patients undergoing cardiac surgery, where respiratory effects could increase risk.
Does a history of asthma increase the risk of mortality and morbidity in patients undergoing elective CABG surgery?
Cohort (n=105)
No
Does a history of asthma increase the risk of mortality and morbidity in patients undergoing elective CABG surgery?
Asthma is associated with longer ICU stays and delayed extubation following elective CABG surgery, highlighting the importance of preoperative asthma control.
Answers are grounded in this paper and cite their sources.
Asthma may extend ICU stay and pulmonary complications after CABG without increasing mortality; leaves open need for larger prospective confirmation.
OBJECTIVES: No studies have been specifically conducted on asthma patients undergoing cardiac surgery for assessing mortality and morbidity. Distinct effects of cardiac surgery lead to negative effects on respiratory functions, putting patients with existing lung diseases under an increased risk. We aimed to investigate whether asthma patients are under higher risk for mortality and possible complications after coronary artery bypass graft (CABG) surgery than patients without asthma. MATERIALS AND METHODS: The study included patients who underwent elective CABG surgery at our hospital between November 2014 and November 2015. Patients with a history of asthma were verified with physical examination and spirometric measurements by a single. The asthma group was compared with the controls in terms of mortality and morbidities. RESULTS: Asthma patients were extubated later than control patients (p=0.028); however, prolonged intubation (longer than 24 h) frequency was not different (p>0.05). Asthma patients required longer stay in the intensive care unit (ICU) (p=0.003) than controls. The incidence of perioperative asthma exacerbations was significantly lower in patients in whom asthma was previously well-controlled. The incidence of postoperative sibilant rhonchi was lower in patients in whom asthma was under control than in those in whom asthma was partially controlled (p=0.020). CONCLUSION: Asthma is associated with longer ICU stay and asthma-related pulmonary complications after CABG surgery. Preoperative evaluation of asthma patients scheduled for CABG surgery requires consideration of the control status of asthma. Studies with more controls are needed to provide further evidence on the topic.
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İlhan et al. (2019) conducted a cohort in Coronary artery disease requiring CABG (n=105). Asthma vs. Non-asthmatic controls was evaluated on Mortality (p=1.000). Asthma did not increase mortality after coronary artery bypass graft surgery compared to controls (3.8% vs 3.8%, p=1.000), but was associated with a significantly longer intensive care unit stay.
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