Key result
Nitrous oxide anesthesia during gynecological surgery did not significantly inhibit platelet function or ADP-induced platelet aggregation.
Why the study?
Does anesthesia with nitrous oxide affect platelet function?
Population
35 patients and in vitro platelet samples
Comparison
Anesthesia with nitrous oxide and direct… vs Baseline (before anesthesia) and in vitro controls
Design
Cohort
Follow-up
90 minutes after beginning of anesthesia and postoperatively
Authors
Loading...
May support nitrous oxide safety regarding platelets in gynecological surgery; leaves open confirmation in randomized trials and other populations.
Observational (n=15)
No
Does anesthesia with nitrous oxide affect platelet function?
Absolute Event Rate: 61.7% vs 58.1%
p-value: p=NS
Anesthesia with nitrous oxide does not significantly inhibit platelet function in vivo or in vitro.
Mamiya et al. (1979) conducted an observational in Gynecological surgery (n=15). Nitrous oxide anesthesia vs. Baseline (before anesthesia) was evaluated on ADP-induced platelet aggregation (%) (p=NS). Nitrous oxide anesthesia during gynecological surgery did not significantly inhibit platelet function or ADP-induced platelet aggregation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: