January 1, 1995European Journal of Cardio-Thoracic Surgery
Regression of pre-existing coronary artery disease in a donor heart after cardiac transplantation
Key result
In a patient receiving an atherosclerotic donor heart, sequential quantitative angiography over 5 years documented regression of a focal right coronary artery lesion from 56% to 13% diameter stenosis.
Why the study?
Does pre-existing coronary artery disease in a donor heart regress after cardiac transplantation?
Population
1 patient with severe congestive heart failure due to dilative cardiomyopathy who underwent urgent heart…
Design
Case_report
Follow-up
5 years
Authors
Discussion
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Implication
Single-case regression of donor coronary stenosis; hypothesis-generating and should not yet change donor acceptance criteria.
Study Design
Type
Case Report (n=1)
Structured PICO
Does pre-existing coronary artery disease in a donor heart regress after cardiac transplantation?
P
Population
1 patient with urgent heart transplantation grafted with an atherosclerotic donor heart followed for 5 years.
E
Exposure
Heart transplantation with an atherosclerotic donor heart
O
Outcome
Regression of pre-existing coronary artery disease assessed by sequential quantitative angiography and intravascular ultrasoundsurrogate
This case report demonstrates that pre-existing coronary artery disease in a donor heart can regress after transplantation, suggesting that atherosclerotic donor hearts may be acceptable for urgent transplantation under strict guidance.
Cite This Study
Haude et al. (1995) conducted a case report in Severe congestive heart failure due to dilative cardiomyopathy (n=1). Heart transplantation with an atherosclerotic donor heart was evaluated on Regression of luminal narrowing of a focal lesion in the right coronary artery. In a patient receiving an atherosclerotic donor heart, sequential quantitative angiography over 5 years documented regression of a focal right coronary artery lesion from 56% to 13% diameter stenosis.