Key result
Electrical stimulation of the rostral pons in cats identified lateral and medial inhibitory areas (mean deltaACTH up to -212 pg/ml, P<0.01) and an intermediate facilitatory area mediating ACTH release.
p-value: p=<0.01
The study maps specific inhibitory and facilitatory areas in the rostral pons that mediate ACTH release in response to hemodynamic changes in a feline model.
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Maps pontine ACTH sites in cats; hypothesis-generating for human hemodynamic stress responses.
Ward et al. (1976) studied this question. Electrical stimulation of the dorsal rostral pons was evaluated on Plasma concentrations of ACTH (deltaACTH) (p=<0.01). Electrical stimulation of the rostral pons in cats identified lateral and medial inhibitory areas (mean deltaACTH up to -212 pg/ml, P<0.01) and an intermediate facilitatory area mediating ACTH release.
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