Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1969ThoraxOpen Access

Ventricular septal defect and aortic regurgitation

View Full Paper
Ask AI
Bookmark
Share

Key result

Surgical correction of ventricular septal defect and aortic regurgitation improved residual regurgitation in 18 of 23 survivors, with a 15% operative mortality in severe cases.

Why the study?

Does surgical management improve outcomes in patients with ventricular septal defect and aortic regurgitation?

Population

29 patients with the association of ventricular septal defect and aortic regurgitation

Design

Case_series

Authors

KHK A Hallidie-SmithHammersmith HospitalEOE. G. J. OlsenSwedish University of Agricultural SciencesCOC M OakleyEvelina London Children's Healthcare

Discussion

Loading...

Member takes

Implication

May support surgical repair in select VSD-AR cases; leaves open optimal timing and selection criteria.

Study Design

Type

Observational (n=29)

Structured PICO

Does surgical management improve outcomes in patients with ventricular septal defect and aortic regurgitation?

P
Population
29 patients with ventricular septal defect and aortic regurgitation, 27 of whom were treated surgically.
E
Exposure
Surgical management (majority had patch closure of the ventricular septal defect and repair of the aortic valve)
O
Outcome
Operative mortality and residual aortic regurgitationhard clinical

Early surgical intervention is desirable for patients with ventricular septal defect and aortic regurgitation due to unpredictable prognosis, high operative risk once heart failure supervenes, and the hazard of infective endocarditis.

Cite This Study

Hallidie-Smith et al. (1969) conducted an observational in Ventricular septal defect and aortic regurgitation (n=29). Surgical correction was evaluated on Operative mortality in patients with severe aortic regurgitation. Surgical correction of ventricular septal defect and aortic regurgitation improved residual regurgitation in 18 of 23 survivors, with a 15% operative mortality in severe cases.

synapsesocial.com/papers/6a9d746334685bd7702a03e2https://doi.org/10.1136/thx.24.3.257

Topics

Heart failureHFrEF treatment
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ventricular Septal Defect with Aortic Regurgitation1964 · 159 citations
  2. 2Ventricular Septal Defect with Aortic Valvular Incompetence1963 · 44 citations
  3. 3Ventricular Septal Defect with Aortic Insufficiency1963 · 43 citations
  4. 4Anatomic and Pathologic Studies in Ventricular Septal Defect1956 · 136 citations
  5. 5VENTRICULAR SEPTAL DEFECT WITH PULMONARY STENOSIS AND AORTIC REGURGITATION1958 · 9 citations