January 11, 2006Journal of Cardiovascular Electrophysiology
Defibrillation Energy Requirements in an ICD Population Receiving Cardiac Resynchronization Therapy
Key result
Successful defibrillation energy requirement testing was achieved in 89% of CRT-D patients, with larger left ventricular inner diameter in diastole (P=0.003) predicting higher energy requirements.
Why the study?
Can defibrillation energy requirement testing be accomplished safely and successfully in patients receiving CRT-D devices, and what predicts higher energy requirements?
Population
501 patients undergoing implant of a cardiac resynchronization therapy with defibrillation capability device
Design
Cohort
Authors
Discussion
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Implication
Supports feasibility of defibrillation testing in most CRT-D patients; larger LV diameter association is hypothesis-generating and requires prospective validation.
Study Design
Type
Observational (n=501)
Structured PICO
Can defibrillation energy requirement testing be accomplished safely and successfully in patients receiving CRT-D devices, and what predicts higher energy requirements?
P
Population
501 patients undergoing implantation of a cardiac resynchronization therapy defibrillator (CRT-D) evaluated retrospectively for defibrillation energy requirements.
E
Exposure
Defibrillation energy requirement (DER) testing during CRT-D implantation
O
Outcome
Defibrillation energy requirements (defined as true threshold or the presence of appropriate safety margins of at least 10 J verified with at least two successful conversions with 21 J or less)surrogate
Defibrillation energy requirement testing can be accomplished safely in most CRT-D patients, though larger left ventricular inner diameter in diastole and prolonged procedure times predict higher energy requirements.
Cite This Study
Schuger et al. (2006) conducted an observational in Patients receiving cardiac resynchronization therapy with defibrillation capability (CRT-D) (n=501). Defibrillation energy requirement (DER) testing during CRT-D implantation was evaluated on Successful DER test outcomes (safety margin ≥10 J verified with ≥2 successful conversions with ≤21 J). Successful defibrillation energy requirement testing was achieved in 89% of CRT-D patients, with larger left ventricular inner diameter in diastole (P=0.003) predicting higher energy requirements.