Key result
Subclinical myocardial dysfunction, present in 34% of patients recovered from COVID-19 pneumonia at 7 months, was a strong independent predictor of long-term MACE (AUC 0.73).
Why the study?
Cardiovascular sequelae, subclinical myocardial dysfunction, and long-COVID symptoms occur after COVID-19, but their long-term prognostic role in patients recovered from COVID-19 pneumonia remained undefined.
Does subclinical myocardial dysfunction predict major adverse cardiovascular events in patients recovered from COVID-19 pneumonia?
Population
110 patients recovered from COVID-19 pneumonia hospitalized at a single institution
Comparison
Subclinical myocardial dysfunction and long-COVID condition vs their absence
Design
Prospective cohort study
Follow-up
21-month clinical follow-up after a 7-month evaluation
Authors
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May support risk stratification with speckle-tracking echo in COVID-19 survivors; hypothesis-generating for intervention trials.
Cohort (n=110)
No
Does subclinical myocardial dysfunction predict major adverse cardiovascular events in patients recovered from COVID-19 pneumonia?
Subclinical myocardial dysfunction assessed by speckle-tracking echocardiography is common in COVID-19 survivors and independently predicts long-term major adverse cardiovascular events.
Cannata et al. (2023) conducted a cohort in COVID-19 pneumonia (n=110). Subclinical myocardial dysfunction vs. No subclinical myocardial dysfunction was evaluated on Major adverse cardiovascular events (MACE), a composite of myocardial infarction, stroke, heart failure hospitalization, and all-cause mortality. Subclinical myocardial dysfunction, present in 34% of patients recovered from COVID-19 pneumonia at 7 months, was a strong independent predictor of long-term MACE (AUC 0.73).
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