Key result
Among patients with pulmonary arterial hypertension, 64% exhibited left ventricular diastolic dysfunction, which was independently predicted by increasing age (OR 1.06) and higher pulmonary artery systolic pressure (OR 1.03).
Population
128 chronic pulmonary arterial hypertension patients, mean age 57 ± 14 years, 77% female. Excluded: history…
Design
Cohort
Authors
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LVDD is prevalent in PAH and linked to age/PASP; leaves open whether it alters prognosis or warrants targeted intervention.
Observational (n=128)
No
Odds Ratio: 1.06 (95% CI 1.03–1.1)
p-value: p=0.001
Impaired left ventricular relaxation is highly prevalent (64%) in patients with pulmonary arterial hypertension and is independently predicted by age and pulmonary artery systolic pressure.
Hernández-Suárez et al. (2017) conducted an observational in Pulmonary arterial hypertension (n=128). Age and pulmonary artery systolic pressure (PASP) was evaluated on Predictors of abnormal left ventricular diastolic function (Age) (OR 1.06, 95% CI 1.03-1.10, p=0.001). Among patients with pulmonary arterial hypertension, 64% exhibited left ventricular diastolic dysfunction, which was independently predicted by increasing age (OR 1.06) and higher pulmonary artery systolic pressure (OR 1.03).
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