Key result
Endoventricular patch plasty for postischemic left ventricular aneurysm yielded 0% mortality at 14 months and improved NYHA class (P=0.0001), compared to 36% mortality with conventional surgery.
Why the study?
Does endoventricular patch plasty improve survival and functional outcomes compared to conventional aneurysmectomy in patients with postischemic left ventricular aneurysm?
Cohort (n=52)
Does endoventricular patch plasty improve survival and functional outcomes compared to conventional aneurysmectomy in patients with postischemic left ventricular aneurysm?
Answers are grounded in this paper and cite their sources.
Endoventricular patch plasty guided by echocardiography significantly improves survival and functional status compared to conventional direct closure for postischemic left ventricular aneurysms.
From May 1985 to December 1991 52 patients were operated upon for postischemic left ventricular aneurysm (LV-A). Between May 1985 and July 1989 25 patients (group I) with a mean age of 59 (46-72) years underwent conventional aneurysmectomy with direct closure of the left ventricle (LV) and a mean of 1.9 (0-3) additional bypass grafts (54% triple-vessel disease). The hospital mortality was 8% (2/25) and the late mortality during a median follow-up time of 34 months was 28% (7/25) with a 4-year survival of 66%. Improvement in the quality of life (NYHA from 2.6 to 2.1, P = 0.078) and global left ventricular ejection fraction (EF) (from 35 to 38%) proved to be unsatisfactory in conjunction with the high late mortality rate. Between August 1989 and December 1991 a prospective series of 27 consecutive patients (group II) with a mean age of 61 (45-71) years underwent endoventricular patch plasty guided by two-dimensional transthoracic echocardiography (TTE) before and after surgery. The patch size and position were calculated preoperatively by measuring the distances from the mitral annulus to the infarct area which were reproduced during surgery with a simple ruler. A mean of 2.1 (0-4) bypass grafts were added with 62% of the patients having triple-vessel disease and 19% left main stenosis (P = 0.05, group I versus II). All patients have survived to date. One patient had to be excluded, giving a median follow-up time of 14 months for 26 patients. At the 6 months' control, the mean NYHA class was improved from 2.7 to 1.6, (P = 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)
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Jakob et al. (1993) conducted a cohort in Postischemic left ventricular aneurysm (n=52). Endoventricular patch plasty vs. Conventional aneurysmectomy with direct closure of the left ventricle was evaluated on Total mortality. Endoventricular patch plasty for postischemic left ventricular aneurysm yielded 0% mortality at 14 months and improved NYHA class (P=0.0001), compared to 36% mortality with conventional surgery.
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