Key result
An MR compatible flow simulator based on a servomotor-driven gear pump successfully generated accurate sinusoidal waveforms up to 10 Hz and realistic aortic flow rates and pressure variations.
The developed MR compatible flow simulator can automatically and accurately generate physiologically realistic pressure and flow waveforms for in vitro testing.
May enable realistic in vitro MR flow testing; leaves open clinical translation.
An MR compatible flow simulator is described which generates physiologically realistic pressure and flow waveforms. The simulator is based on a servomotor-driven gear pump which produces pulsatile flow by modulation of the servomotor rotation rate. Operation of the simulator is under the control of a personal computer, which executes an iterative feedback loop to minimize errors between measured and desired pressure waveforms. The simulator is totally automatic, requiring only a few minutes of iteration to generate the desired pressure waveform. Accurate sinusoidal waveforms with frequencies up to 10 Hz have been generated using the simulator, with high-frequency contamination of the measured waveform at least 80 dB below the fundamental frequency. Aortic waveforms have been produced with realistic flow rates and pressure variations. The pump assembly is mechanically straightforward and can operate at an 8-m distance from the flow phantom to allow the device to be isolated from the MR magnet room.
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Plewes et al. (1995) studied this question. MR compatible flow simulator was evaluated on Generation of physiologically realistic pressure and flow waveforms. An MR compatible flow simulator based on a servomotor-driven gear pump successfully generated accurate sinusoidal waveforms up to 10 Hz and realistic aortic flow rates and pressure variations.
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