Key result
Maternal administration of diclofenac at 36 weeks gestation caused reversible fetal ductus arteriosus vasoconstriction and right ventricular hypertension.
Why the study?
Does diclofenac administration in late pregnancy induce contraction of the fetal ductus arteriosus?
Population
1 pregnant woman at 36 weeks gestation and her fetus
Design
Case_report
Authors
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Suggests caution with diclofenac near term; hypothesis-generating case leaves open need for prospective confirmation.
Case Report (n=1)
Does diclofenac administration in late pregnancy induce contraction of the fetal ductus arteriosus?
Diclofenac use in late pregnancy can cause reversible constriction of the fetal ductus arteriosus, highlighting the need for fetal echocardiography monitoring if used.
Rein et al. (1999) conducted a case report in Fetal ductus arteriosus contraction (n=1). Diclofenac was evaluated on Fetal ductus arteriosus vasoconstriction and right ventricular hypertension. Maternal administration of diclofenac at 36 weeks gestation caused reversible fetal ductus arteriosus vasoconstriction and right ventricular hypertension.
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