Key result
Isoproterenol and dipyridamole increased aorto-coronary vein bypass flow by a mean of 70% and 49% respectively, while isosorbide dinitrate had no influence on flow.
Why the study?
Do vasoactive drugs (papaverine, isoproterenol, dipyridamole, isosorbide dinitrate) improve aorto-coronary vein bypass flow in patients undergoing bypass surgery?
Population
20 patients with an aorto-coronary vein bypass
Design
Case_series
Follow-up
first postoperative days
Authors
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May increase intraoperative graft flow; case report leaves open need for controlled trials on clinical outcomes.
Do vasoactive drugs (papaverine, isoproterenol, dipyridamole, isosorbide dinitrate) improve aorto-coronary vein bypass flow in patients undergoing bypass surgery?
Isoproterenol, dipyridamole, and papaverine significantly increase aorto-coronary vein bypass flow, whereas isosorbide dinitrate does not.
Bertranou et al. (1973) studied aorto-coronary vein bypass (n=20). papaverine hydrochloride, isoproterenol, dipyridamole, and isosorbide dinitrate was evaluated on vein bypass flow. Isoproterenol and dipyridamole increased aorto-coronary vein bypass flow by a mean of 70% and 49% respectively, while isosorbide dinitrate had no influence on flow.
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