Key result
In a canine model of myocardial ischemia, reperfusion did not increase the transmurality or advance the epicardial edge of necrosis compared with nonreperfusion.
Why the study?
Does reperfusion extend necrosis in a canine model of myocardial ischemia?
Does reperfusion extend necrosis in a canine model of myocardial ischemia?
In a canine model, reperfusion did not extend myocardial necrosis compared to nonreperfusion within the same ischemic territory.
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Reperfusion does not extend necrosis in this canine model; leaves open translation to human reperfusion injury.
Ganz et al. (1990) studied Myocardial ischemia (n=20). Reperfusion vs. Nonreperfusion was evaluated on Transmurality of necrosis. In a canine model of myocardial ischemia, reperfusion did not increase the transmurality or advance the epicardial edge of necrosis compared with nonreperfusion.
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