Key result
Genetically resistant chickens developed higher levels of serum neutralizing antibodies than susceptible chickens after inoculation with Marek's disease virus.
Population
Genetically resistant and susceptible line chickens inoculated with JM strain of Marek's disease virus at…
Comparison
Inoculation with JM strain of Marek's disease… vs Genetically susceptible line chickens compared…
Design
Preclinical
Authors
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Higher neutralizing antibodies may guide poultry breeding for Marek's resistance; leaves open translational relevance to other species or vaccines.
In chickens exposed to Marek's disease, higher serum neutralizing antibody levels correlate with genetic resistance to the disease and oncogenicity.
Hong et al. (1974) studied Marek's disease. Genetic resistance vs. Genetic susceptibility was evaluated on Serum neutralizing antibody levels. Genetically resistant chickens developed higher levels of serum neutralizing antibodies than susceptible chickens after inoculation with Marek's disease virus.
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