Key result
Marginal excision, tumor necrosis, and extracompartmental location increased local recurrence risk, while local recurrence, Grade IV, male sex, tumor necrosis, and tumor size decreased survival.
Why the study?
What are the prognostic variables for local recurrence and survival in patients with highly malignant soft tissue sarcoma of the locomotor system?
Population
144 patients with highly malignant (histologic Grades III and IV) soft tissue sarcoma of the locomotor system
Design
Cohort
Follow-up
minimum 6 years, or until death
Authors
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These factors may stratify recurrence and survival risk in soft tissue sarcoma; leaves open prospective validation before guiding management.
Cohort (n=144)
What are the prognostic variables for local recurrence and survival in patients with highly malignant soft tissue sarcoma of the locomotor system?
In highly malignant soft tissue sarcomas, specific tumor characteristics and surgical margins are key prognostic factors for recurrence and survival.
Rööser et al. (1987) conducted a cohort in Highly malignant soft tissue sarcoma of the locomotor system (n=144). Prognostic factors (e.g., marginal excision, tumor necrosis, extracompartmental location) was evaluated on Local recurrence and survival. Marginal excision, tumor necrosis, and extracompartmental location increased local recurrence risk, while local recurrence, Grade IV, male sex, tumor necrosis, and tumor size decreased survival.
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